Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications
نویسندگان
چکیده
منابع مشابه
Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications.
BACKGROUND In women, anti-Müllerian hormone (AMH) is exclusively produced by granulosa cells of ovarian follicles during the early stages of follicle development. After an initial increase until early adulthood, AMH concentrations slowly decrease with increasing age until becoming undetectable ∼5 years before menopause when the stock of primordial follicles is exhausted. However, major individu...
متن کاملAssessment of ovarian reserve in adult childhood cancer survivors using anti-Müllerian hormone.
BACKGROUND The aim was to assess possible treatment-induced gonadal damage in a cohort of adult female childhood cancer survivors (CCS) using anti-Müllerian hormone (AMH), the most sensitive marker of ovarian reserve. METHODS A total cohort of 185 survivors was compared with 42 control subjects. The median follow-up time was 18.1 years (range 4.1-43.2 year). RESULTS Median AMH concentration...
متن کاملSerum anti-Müllerian hormone levels: a novel measure of ovarian reserve.
BACKGROUND Anti-Müllerian hormone (AMH) is produced by the granulosa cells of preantral and small antral follicles and its levels can be assessed in serum. Since the number of ovarian follicles declines with increasing age, AMH levels might be used as a marker for ovarian ageing. Therefore, we studied the relationship between AMH levels and ovarian response during ovarian stimulation for IVF. ...
متن کاملEvaluation of Ovarian Reserve with Anti-Müllerian Hormone in Familial Mediterranean Fever
Objective. To investigate ovarian reserves in attack-free familial Mediterranean fever (AF-FMF) patients at the reproductive age by anti-Müllerian hormone (AMH), antral follicle count (AFC), ovarian volume, and hormonal parameters. Methods. Thirty-three AF-FMF patients aging 18-45 years and 34 healthy women were enrolled and FSH, LH, E2, PRL, and AMH levels were measured in the morning blood sa...
متن کاملRegulation of ovarian function: the role of anti-Müllerian hormone.
Anti-Müllerian hormone (AMH), also known as Müllerian inhibiting substance, is a member of the transforming growth factor beta superfamily of growth and differentiation factors. In contrast to other members of the family, which exert a broad range of functions in multiple tissues, the principal function of AMH is to induce regression of the Müllerian ducts during male sex differentiation. Howev...
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ژورنال
عنوان ژورنال: Human Reproduction Update
سال: 2014
ISSN: 1355-4786,1460-2369
DOI: 10.1093/humupd/dmu020